There is a document (WORD or PDF) available for this assignment on the left menu under Readings/Practice. This is due Tuesday, July 15. That is a hard deadline, as the course ends!
Question 1
1. Go to Ensembl and find angiotensin converting enzyme genes in zebrafish.
a. Give the chromosome number for both the ace2 and ace genes.
Question 2
1. Go to Ensembl and find angiotensin converting enzyme genes in zebrafish.
b. How many transcripts are listed for ace2?
Question 3
1. Go to Ensembl and find angiotensin converting enzyme genes in zebrafish.
c. Click splice variants for the ace2 gene. This is a reverse strand gene so read right to left. Which transcript has the more upstream stop codon?
Question 4
Go to Ensembl and find angiotensin converting enzyme genes in zebrafish.
d. Access the longer transcript of the ace2 gene. How many coding exons (includes partially coding)?
Question 5
1. Go to Ensembl and find angiotensin converting enzyme genes in zebrafish.
e. Looking at the Variation Table for ace2, how many SNPs are shown?
PUT ONLY A NUMBER IN YOUR ANSWER....DO NOT ADD WORDS OR SPELL IT OUT!
Answer for Question 5
Question 6
1. Go to Ensembl and find angiotensin converting enzyme genes in zebrafish.
f. How many of those ace2 SNPs affect the protein sequence?
PUT ONLY A NUMBER IN YOUR ANSWER. DO NOT ADD WORDS OR SPELL OUT THE NUMBER!
Answer for Question 6
Question 7
2. Use the following table (https://d396qusza40orc.cloudfront.net/bioinform/assignments/CODIS.docx) to answer paternity questions.The document is available under the Readings/Practice link on the left menu
a. Which males can be eliminated from paternity consideration based on the D8S1179 locus only ?
Question 8
2. Use the following table (https://d396qusza40orc.cloudfront.net/bioinform/assignments/CODIS.docx) to answer paternity questions.The document is available under the Readings/Practice link on the left menu
b. Which are the potential father(s) based on the entire results (all six loci)??
Question 9
3. Access the annotation at https://d396qusza40orc.cloudfront.net/bioinform/assignments/week_5.txt. Examine the mRNA and CDS regions.
a. How many exons are in the transcript?
YOUR ANSWER SHOULD BE A NUMBER. DO NOT ADD WORDS. DO NOT SPELL OUT THE NUMBER!
Answer for Question 9
Question 10
3. Access the annotation at https://d396qusza40orc.cloudfront.net/bioinform/assignments/week_5.txt. Examine the mRNA and CDS regions.
b. What is the numerical location of an intron that is lies completely within an untranslated region?