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Question 1

Which of the following correctly describes polycistronic mRNA?

Because there can be multiple coding regions per transcript, all but one coding region must be spliced out.

There are multiple transcription start sites for a single gene.

There are multiple mRNA molecules made from a single gene.

There can be more than one coding region present on a single mRNA molecule.

Question 2

Which of the following has the smallest genome?

Human

Tomato plant

Human immunodeficiency virus

Worm

Question 3

Which best describes a typical bacterial genome (ignoring plasmids)?

Circular single-stranded DNA

Linear double-stranded DNA

Linear single-stranded RNA

Circular double-stranded DNA

Question 4

What three genes are usually found in retroviruses?

gag, dpy, BRCA1

gag, pol, env

gag, pol, BRCA1

gag, dpy, env

Question 5

Which of the following is a program focused on predicting gene locations in bacterial genomes?

Delta-BLAST

PSI-BLAST

Glimmer

LALIGN

Question 6

In a gene model, the +1 position refers to what?

the 3' UTR

the start codon

the transcription start site

the ribosome binding site

Question 7

When looking at DNA locations, what best describes the term "upstream?"

In the 3' UTR of a transcript.

In the direction of the 5' end of the DNA strand.

In the direction of the 3' side of the DNA strand.

In the 5' UTR of a transcript.

Question 8

Which best describes the 5' UTR of a transcript?

The intron.

The mRNA region that is downstream from the last stop codon of translation.

The region of DNA just upstream from the transcription start site.

The mRNA region that is upstream from the first start codon of translation.

Question 9

Which best describes how subtypes of Influenza A Virus are named?

The type of hemagglutinin and type of neuraminidase

The type of hemagglutinin and the number of neuraminidase genes.

The number of hemagglutinin genes and the type of neuraminidase.

The number of hemagglutinin genes and the number of neuraminidase genes.

Question 10

Which is the best explanation for why a bacterial gene prediction might turn out to be incorrect?

Gene prediction programs are not 100% accurate.

Protein sequences are necessary and absolutely essential for correct prediction.

There must have been an input error.

Because bacterial DNA is polycistronic, it is impossible for gene predictors to predict that.

In accordance with the Coursera Honor Code, I (Anonymous Student) certify that the answers here are my own work.

You cannot submit your work until you agree to the Honor Code. Thanks!

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Bioinformatics: Life Sciences on Your Computer
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