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Question 1

A high-frequency match warning on a PROSITE pattern hit means that:

The pattern is short and occurs frequently in proteins.

The E value is too high to be meaningful.

The pattern is long and difficult to match.

The result is a false positive.

Question 2

Secondary structure prediction programs are designed to predict:

The placement of beta-strands in three-dimensional space

The psi- and phi- angles of bonds for the central alpha-carbon

Which amino acids are found in alpha-helices or beta-strands

The complete 3-D structure of a protein

Question 3

Which statement is true about patterns that represent protein motifs?

Patterns are represented by neural networks.

Patterns are qualitative, and pattern hits are not assigned E values.

Patterns are the basis of PSI-BLAST.

Patterns quantitatively represent protein motifs.

Question 4

If a protein were reported to be 14,560 daltons, that measure refers to its _______________________.

Resolution

Secondary structure

Length of carbon backbone

Molecular weight

Question 5

Which describes a protein's isoelectric point?

The pH at which every atom in the protein is uncharged.

The pH at which a protein has no net charge.

The voltage required to get the protein through a gel.

The net charge at pH 7.0

Question 6

The Protein Bank (PDB) is a database centered primarily around _______________________

Protein molecular weights

Protein localizations

Protein structures

Protein lengths

Question 7

There are FAR more protein sequences in sequence databases than there are protein structures in structure databases. What is the primary reason for this.

Some translated proteins have no protein structure.

A very low fraction of protein sequences have structure data.

Some protein structures have no protein sequence.

There is a huge backlog in protein structure databases.

Question 8

Localization programs such as Predotar and CELLO are designed to predict _________________

Protein motifs and domains, based on its sequence.

Where a protein goes after translation, based on its sequence.

Where a protein goes after translation, based on its 3-D structure.

Protein isoelectric point, based on its 3-D structure

Question 9

Which is a type of protein secondary structure?

Isoelectric point

3-D structure

Localization

Beta strand

Question 10

Which of the following is predicted using the pI/Mw tool?

Isoelectric Point

Mann-Whitney

3-D Structure

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Bioinformatics: Life Sciences on Your Computer
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